Thanks for everyone who rose to the challenge so far! Great fun to see your interpretations/manipulations/twists on the character!
I've tried to comment on each below.

Your images won't be included in my quote (a security limitation of GC I think), so I trimmed down each comment a bit for compactness (see the original by scrolling up).
oldmangrumpy wrote:
Made some changes as follows:
1 facial colour
2 cat eyes & bushier eyebrows
3 under eye and cheek contours
4 nose ring
5 extended background colouring to both sides
6 finished off the jacket hood on top
Thanks for the opportunity Griatch.
This gives me a bit of a 'Wicked witch of the West" vibe

Very wicked indeed!
sallyanne wrote:
Twins?
In Gmic I did a kaliedescope 'symmetry'. Changed the hue and added a tree to her forehead.
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By the way thanks for the play. I hope I didn't ruin her too much
Interesting variation with both her head and the tree showing a sort of fractal properties almost. Her red eyes also contrasts nicely with the green of the tree here.
Rod wrote:
I ran my Random Paint Strokes script on the image (i used SUBTRACT MODE).
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Sort of a dark Zombie look i think.

It strikes me as looking a bit like video artifacting, which is spooky on its own (reminds me of those analogue/liminal horror videos!)
Tas_mania wrote:
I've been experimenting with layer modes specifically 'difference'. This one was similar to what I was doing.
This feels bit like 80s CRT monitor washout; which makes for a spooky effect if seeing on a screen!
teapot wrote:
Even inscrutable androids have tells, I wonder what happens when her eye goes red.
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Hah, good point, probably nothing good happens then!
(In fact, in the adjoining story, she deliberately makes a point of avoiding having a red eye because she thinks it makes her look too much like the Terminator.)
MareroQ wrote:
Thanks for sharing.
A little fun with symmetry
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and more with G'MIC:
Pencil Portrait
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Felt Pen (plus mod Difference)
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Considering her face is overall symmetric, it's fascinating how different and unusual it looks when the light/shadows are also symmetric. I suppose the first symmetry image (light side mirrored) is more understandable - she's just well-lit, whereas the second one feels very eery because there is no natural situation where you'd get this kind of light from the front while retaining the shadows).
The various pen filters makes for cool effects, I think I like the second pencil portrait the most; it's like she's in the white noice of a TV
Wallace wrote:
[align=center]Not sure if you can tell what's been done,
but here it is.
I took a screenshot of my workspace.]
Thanks for sharing the layer layout too! The 'cyber' overlays and CRT effects work well here. Poor girl having a crosshair on her (or is it a camera focus?)!
neurolurker wrote:
Attachment:
for griatch with thanks.jpg
Thanks for the invitation to participate.
Ooh, text! And little spooky after-images of her face. She could certainly say that, I bet! Like the font chosen too.
teapot wrote:
Attachment:
griatch-cal-art-challenge-01.jpg
Attachment:
griatch-cal-art-challenge-02.jpg
Nice one, this manipulation sort of makes her face all the more intense.